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1

Diethyl bromodifluoromethylphosphonate: a highly efficient and environmentally benign difluorocarbene precursor

Yossi Zafrani, Gali Sod-Moriah, Yoffi Segall

Journal:

Year:

2009

Language:

english

File:

PDF, 674 KB

english, 2009

2

Selective Inhibitors of Fatty Acid Amide Hydrolase Relative to Neuropathy Target Esterase and Acetylcholinesterase: Toxicological Implications

Gary B. Quistad, Susan E. Sparks, Yoffi Segall, Daniel K. Nomura, John E. Casida

Journal:

Toxicology and Applied Pharmacology

Year:

2002

Language:

english

File:

PDF, 65 KB

english, 2002

3

Composition of technical ethephon [(2-chloroethyl)phosphonic acid] and some analogs relative to their reactivity and biological activity

Segall, Yoffi, Grendell, Richard L., Toia, Robert F., Casida, John E.

Journal:

Journal of Agricultural and Food Chemistry

Year:

1991

Language:

english

File:

PDF, 778 KB

english, 1991

4

Protection against tabun toxicity in mice by prophylaxis with an enzyme hydrolyzing organophosphate esters

Lily Raveh, Yoffi Segall, Haim Leader, Nathan Rothschild, Dan Levanon, Yigal Henis, Yacov Ashani

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 431 KB

english, 1992

5

Stable acyloxy-chlorophosphorane obtained from 2-(diphenylphosphinyl)-benzoic acid and thionyl chloride

Granoth, Itshak, Alkabets, Rivka, Segall, Yoffi

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1981

Language:

english

File:

PDF, 162 KB

english, 1981

6

Synthesis of Stable Spirooxyphosphoranes - Potential Promoters of Catalytic Antibodies

Nir, Osnat, Fridkin, Mati, Segall, Yoffi

Journal:

Phosphorus Sulfur and Silicon and the Related Elements

Year:

1996

Language:

english

File:

PDF, 252 KB

english, 1996

7

Syntheses of cyclic acyloxyphosphoranes from phosphine oxides: spectroscopy, stability, and molecular structure. A stable P-hydroxyphosphorane: 1-hydroxy-1,1'-spirobi[3H-2,1-benzoxaphosphole]-3,3'-dione

Segall, Yoffi, Granoth, Itshak

Journal:

Journal of the American Chemical Society

Year:

1978

Language:

english

File:

PDF, 645 KB

english, 1978

8

Preparation of a dibenzo[b,e]phosphorin. Selective phosphine oxide reduction by trichlorosilane

Segall, Yoffi, Granoth, Itshak, Kalir, Asher

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1974

Language:

english

File:

PDF, 120 KB

english, 1974

9

Organophosphoro(thioperoxoic) acids: Direct observation and reactivity

Yoffi Segall, Shao-Yong Wu, Robert F. Toia, John E. Casida

Journal:

Tetrahedron Letters

Year:

1990

Language:

english

File:

PDF, 191 KB

english, 1990

10

Prophylaxis against organophsphate poisoning by an enzyme hydrolysing organophosphorus compounds in mice

Yacov Ashani, Nathan Rothschild, Yoffi Segall, Dan Levanon, Lily Raveh

Journal:

Year:

1991

Language:

english

File:

PDF, 537 KB

english, 1991

11

Hydroxyphosphorane intermediates in substitution reactions at phosphorus in acyclic phosphonofluoridates: evidence from nuclear magnetic resonance

Granoth, Itshak, Segall, Yoffi, Waysbort, Daniel, Shirin, Ezra, Leader, Haim

Journal:

Journal of the American Chemical Society

Year:

1980

Language:

english

File:

PDF, 431 KB

english, 1980

12

Nucleophilic Transformation of Cyclic Phosphate Triesters.

Nissan Ashkenazi, Yishai Karton, Yoffi Segall

Journal:

Year:

2005

File:

PDF, 15 KB

2005

13

Oxidative conversion of phosphorothiolates to phosphinyloxysulfonates probably via phosphorothiolate s-oxides

Yoffi Segall, John E. Casida

Journal:

Tetrahedron Letters

Year:

1982

Language:

english

File:

PDF, 265 KB

english, 1982

14

Function-specific blockage of M1 and M3 muscarinic acetylcholine receptors by VX and echothiophate

Zipora Pittel, Dov Barak, Yoffi Segall

Journal:

Year:

2006

Language:

english

File:

PDF, 475 KB

english, 2006

15

Direct determination of the chemical composition of acetylcholinesterase phosphonylation products utilizing electrospray-ionization mass spectrometry

Ruth Barak, Arie Ordentlich, Dov Barak, Meir Fischer, Hendrik P Benschop, Leo P.A De Jong, Yoffi Segall, Baruch Velan, Avigdor Shafferman

Journal:

Year:

1997

Language:

english

File:

PDF, 637 KB

english, 1997

16

Carbocation-Mediated Processes in Biocatalysts. Contribution of Aromatic Moieties

Barak, Dov, Ordentlich, Arie, Segall, Yoffi, Velan, Baruch, Benschop, Hendrik P., De Jong, Leo P. A., Shafferman, Avigdor

Journal:

Journal of the American Chemical Society

Year:

1997

Language:

english

File:

PDF, 142 KB

english, 1997

17

Novel specific carbon?carbon bond formation; substituent and solvent effects associated with hydride addition to aromatic olefins

Granoth, Itshak, Alkabets, Rivka, Segall, Yoffi, Rachaman, Eliezer, Leader, Haim

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1975

Language:

english

File:

PDF, 175 KB

english, 1975

18

Arachidonylsulfonyl derivatives as cannabinoid CB1 receptor and fatty acid amide hydrolase inhibitors

Yoffi Segall, Gary B. Quistad, Daniel K. Nomura, John E. Casida

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 132 KB

english, 2003

19

Aged and non-aged pyrenebutyl-containing organophosphoryl conjugates of chymotrypsin: Preparation and comparison by 31P-NMR spectroscopy

Jacob Grunwald, Yoffi Segall, Ezra Shirin, Daniel Waysbort, Nitza Steinberg, Israel Silman, Yacov Ashani

Journal:

Biochemical Pharmacology

Year:

1989

Language:

english

File:

PDF, 1.21 MB

english, 1989

20

Oxidation of sulfallate and related alkyl dialkyldithiocarbamates to dialkylformamides via sulfine and iminium ion intermediates

Segall, Yoffi, Casida, John E.

Journal:

Journal of Agricultural and Food Chemistry

Year:

1983

Language:

english

File:

PDF, 667 KB

english, 1983

21

Friedel?Crafts acylation?cyclisation reactions of 3-bromophenyl ethers with phosphorus trichloride and oxalyl chloride to give the corresponding phenoxaphosphine and xanthen-9-one derivatives

Granoth, Itshak, Segall, Yoffi, Kalir, Asher

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1973

File:

PDF, 350 KB

1973

22

Cannabinoid CB1 Receptor Chemical Affinity Probes: Methods Suitable for Preparation of Isopropyl [11,12-3H]Dodecylfluorophosphonate and [11,12-3H]Dodecanesulfonyl Fluoride

Yoffi Segall, Gary B. Quistad, John E. Casida

Journal:

Year:

2003

File:

PDF, 54 KB

2003

23

Reaction of lithium aluminium hydride with alternant aromatic olefins

Granoth, Itshak, Segall, Yoffi

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1974

Language:

english

File:

PDF, 133 KB

english, 1974

24

-Oxide Intermediates with Alcohols

Segall, Yoffi, Casida, John E.

Journal:

Phosphorous and Sulfur and the Related Elements

Year:

1983

Language:

english

File:

PDF, 345 KB

english, 1983

25

Resolving Pathways of Interaction of Covalent Inhibitors with the Active Site of Acetylcholinesterases: MALDI-TOF/MS Analysis of Various Nerve Agent Phosphyl Adducts

Elhanany, Eytan, Ordentlich, Arie, Dgany, Or, Kaplan, Dana, Segall, Yoffi, Barak, Ruth, Velan, Baruch, Shafferman, Avigdor

Journal:

Chemical Research in Toxicology

Year:

2001

Language:

english

File:

PDF, 102 KB

english, 2001

26

Mechanism for the mutagenic activation of the herbicide sulfallate

Rosen, Joseph D., Schuphan, Ingolf, Segall, Yoffi, Casida, John E.

Journal:

Journal of Agricultural and Food Chemistry

Year:

1980

Language:

english

File:

PDF, 271 KB

english, 1980

27

Product control in nucleophilic substitution at tetrahedral phosphorus by the relative apicophilicity of the nucleophile

Granoth, Itshak, Segall, Yoffi, Leader, Haim

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1976

Language:

english

File:

PDF, 140 KB

english, 1976

28

ChemInform Abstract: Diethyl Bromodifluoromethylphosphonate: A Highly Efficient and Environmentally Benign Difluorocarbene Precursor.

Yossi Zafrani, Gali Sod-Moriah, Yoffi Segall

Journal:

Year:

2009

File:

PDF, 30 KB

2009

29

The Mechanism of Nucleophilic Displacements at Phosphorus in Chloro-Substituted Methylphosphonate Esters: P−O vs P−C Bond Cleavage: A DFT Study

Ashkenazi, Nissan, Segall, Yoffi, Chen, Ravit, Sod-Moriah, Gali, Fattal, Eyal

Journal:

Journal of Organic Chemistry

Year:

2010

Language:

english

File:

PDF, 2.57 MB

english, 2010

30

Chemical consequences of hydride addition to aromatic olefins

Granoth, Itshak., Segall, Yoffi., Leader, Haim., Alkabets, Rivka.

Journal:

Journal of Organic Chemistry

Year:

1976

Language:

english

File:

PDF, 875 KB

english, 1976

31

Cannabinoid CB1 Receptor Chemical Affinity Probes: Methods Suitable for Preparation of Isopropyl [11,12- 3 H]Dodecylfluorophosphonate and [11,12- 3 H]Dodecanesulfonyl Fluoride

Segall, Yoffi, Quistad, Gary B., Casida, John E.

Journal:

Synthetic Communications

Year:

2003

Language:

english

File:

PDF, 195 KB

english, 2003

32

3-Substituted 2-halopropenals: mutagenicity, detoxification and formation from 3-substituted 2,3-dihalopropanal promutagens

Yoffi Segall, Ella C. Kimmel, David R. Dohn, John E. Casida

Journal:

Mutation Research/Genetic Toxicology

Year:

1985

Language:

english

File:

PDF, 547 KB

english, 1985

33

Exploring the Active Center of Human Acetylcholinesterase with Stereomers of an Organophosphorus Inhibitor with Two Chiral Centers †

Ordentlich, Arie, Barak, Dov, Kronman, Chanoch, Benschop, Hendrik P., De Jong, Leo P. A., Ariel, Naomi, Barak, Ruth, Segall, Yoffi, Velan, Baruch, Shafferman, Avigdor

Journal:

Year:

1999

Language:

english

File:

PDF, 173 KB

english, 1999

34

Enzyme Engineering Towards Novel Op-Hydrolases Based on the Human Acetylcholinesterase Template

Shafferman, Avigdor, Ordentlich, Arie, Barak, Dov, Kronman, Chanoch, Grosfeld, Haim, Stein, Dana, Ariel, Naomi, Segall, Yoffi, Velan, Baruch

Journal:

Phosphorus Sulfur and Silicon and the Related Elements

Year:

1996

Language:

english

File:

PDF, 275 KB

english, 1996

35

SYNTHESIS, REACTIVITY AND CONFORMATION OF 10,11-DIHYDRODIBENZO-[ b,f ]PHOSPHEPIN AND DIBENZO[ b,f ]PHOSPHEPIN DERIVATIVES. PHOSPHORUS ANALOGUES OF IMINOBIBENZYL ANTIDEPRESSANTS

Segall, Yoffi, Shirin, Ezra, Granoth, Itshak

Journal:

Phosphorous and Sulfur and the Related Elements

Year:

1980

Language:

english

File:

PDF, 903 KB

english, 1980

36

Selective site controlled nucleophilic attacks in 5-membered ring phosphate esters: unusual C–O vs. common P–O bond cleavage

Ashkenazi, Nissan, Zade, Sanjio S., Segall, Yoffi, Karton, Yishai, Bendikov, Michael

Journal:

Chemical Communications

Year:

2005

Language:

english

File:

PDF, 204 KB

english, 2005

37

Stereoselectivity toward VX Is Determined by Interactions with Residues of the Acyl Pocket as Well as of the Peripheral Anionic Site of AChE †

Ordentlich, Arie, Barak, Dov, Sod-Moriah, Gali, Kaplan, Dana, Mizrahi, Dana, Segall, Yoffi, Kronman, Chanoch, Karton, Yishai, Lazar, Arie, Marcus, Dino, Velan, Baruch, Shafferman, Avigdor

Journal:

Year:

2004

Language:

english

File:

PDF, 490 KB

english, 2004

38

Nucleophilic transformations of cyclic phosphate triesters

Nissan Ashkenazi, Yishai Karton, Yoffi Segall

Journal:

Tetrahedron Letters

Year:

2004

Language:

english

File:

PDF, 269 KB

english, 2004

39

Studies of the Synthesis of Diethyl Cyclopropylphosphonate and Its Thio and Seleno Analogs

Zafrani, Yossi, Chen, Ravit, Ashkenazi, Nissan, Segall, Yoffi

Journal:

Synthetic Communications

Year:

2008

Language:

english

File:

PDF, 155 KB

english, 2008

40

Cannabinoid CB1 receptor as a target for chlorpyrifos oxon and other organophosphorus pesticides

Gary B. Quistad, Daniel K. Nomura, Susan E. Sparks, Yoffi Segall, John E. Casida

Journal:

Toxicology Letters

Year:

2002

Language:

english

File:

PDF, 104 KB

english, 2002

41

Evidence for P−N Bond Scission in Phosphoroamidate Nerve Agent Adducts of Human Acetylcholinesterase †

Barak, Dov, Ordentlich, Arie, Kaplan, Dana, Barak, Ruth, Mizrahi, Dana, Kronman, Chanoch, Segall, Yoffi, Velan, Baruch, Shafferman, Avigdor

Journal:

Year:

2000

Language:

english

File:

PDF, 105 KB

english, 2000

42

ChemInform Abstract: FRIEDEL-CRAFTS ACYLATION-CYCLISATION REACTIONS OF 3-BROMOPHENYL ETHERS WITH PHOSPHORUS TRICHLORIDE AND OXALYL CHLORIDE TO GIVE THE CORRESPONDING PHENOXAPHOSPHINE AND XANTHEN-9-ONE DERIVATIVES

GRANOTH, ITSHAK, SEGALL, YOFFI, KALIR, ASHER

Journal:

Chemischer Informationsdienst

Year:

1973

File:

PDF, 153 KB

1973

43

α-AMINO ACID DERIVED BISPHOSPHONATES. SYNTHESIS AND ANTI-RESORFTIVE ACTIVITY

Mizrahi, Dana M., Waner, Trevor, Segall, Yoffi

Journal:

Phosphorus Sulfur and Silicon and the Related Elements

Year:

2001

Language:

english

File:

PDF, 908 KB

english, 2001

44

Surprising synthesis and reactivity of an acidic hydroxyphosphorane

Segall, Yoffi, Granoth, Itshak

Journal:

Journal of the American Chemical Society

Year:

1979

Language:

english

File:

PDF, 251 KB

english, 1979

45

Peracid-mediated n-oxidation and rearrangement of dimethylphosphoramides: plausible model for oxidative bioactivation of the carcinogen hexamethylphosphoramide (HMPA)

Ian Holden, Yoffi Segall, Ella C. Kimmel, John E. Casida

Journal:

Tetrahedron Letters

Year:

1982

Language:

english

File:

PDF, 263 KB

english, 1982

46

The role of AChE active site gorge in determining stereoselectivity of charged and noncharged VX enantiomers

Arie Ordentlich, Dov Barak, Gali Sod-Moriah, Dana Kaplan, Dana Mizrahi, Yoffi Segall, Chanoch Kronman, Yishai Karton, Arie Lazar, Dino Marcus, Baruch Velan, Avigdor Shafferman

Journal:

Chemico-Biological Interactions

Year:

2005

Language:

english

File:

PDF, 192 KB

english, 2005

47

OXIDATIVELY-INDUCED FORMATION OF DIALKYL HYDROGENPHOSPHONATES FROM PHOSPHOROTHIONATES

Wu, Shao-Yong, Segall, Yoffi, Sanders, Mark, Toia, Robert F., Casida, John E.

Journal:

Phosphorus Sulfur and Silicon and the Related Elements

Year:

1990

Language:

english

File:

PDF, 254 KB

english, 1990

48

Corrigenda

Granoth, Itshak, Segall, Yoffi, Leader, Haim, Veech, Joseph A., Stipanovic, Robert D., Bell, Alois A.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1976

File:

PDF, 36 KB

1976

49

Exceptionally stable oxyphosphoranes. Intramolecular nucleophilic attack by a phosphine oxide on a carboxylic carbonyl group

Segall, Yoffi, Granoth, Itshak, Kalir, Asher, Bergmann, Ernst D.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1975

Language:

english

File:

PDF, 126 KB

english, 1975

50

Friedel?Crafts acylation?cyclisation reactions of 3-bromophenyl ethers with phosphorus trichloride and oxalyl chloride to give the corresponding phenoxaphosphine and xanthen-9-one derivatives

Granoth, Itshak, Segall, Yoffi, Kalir, Asher

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1973

Language:

english

File:

PDF, 350 KB

english, 1973

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